The Effect of Ultrasound-Guided Erector Spinae Plane Block on Postoperative Analgesia in Percutaneous Nephrolithotomy

Istanbul University56 enrolled

Overview

This study is planned as a single-center randomized single blinded study and includes patients undergoing percutaneous nephrolitotomy.The aim of the study is to evaluate the effect of ultrasound guided erector spinal plane block on postoperative analgesia in percutaneous nephrolitotomy. Primary outcome is the total 24 hour morphine consumption.

Adult patients aged 18-65 years with American Society of Anesthesiologists (ASA) physical status I-II scheduled for elective PCNL were allocated to receive either a unilateral ultrasound-guided ESPB at the T9 level with 20 mL of 0.25% bupivacaine followed by postoperative IV morphine PCA (Group ESPB ) or postoperative IV morphine PCA alone (Group C). 24 hour morphine consumption, numeric Rating Scale (NRS) pain scores, rescue analgesic requirements, sedation scores, opioid-related adverse effects, hospital stay, chronic pain, patient and surgeon satisfaction are recorded.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Acute Postoperative Pain in Urological Surgery Regional Anaesthesia

Interventions

Erector Spinae Plane BlockPROCEDURE

Erector spinae plane block is applied in longitudinal plane at T9 level.

Intravenous analgesiaPROCEDURE

Inravenous morphine is administered via patient controlled analgesia device.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Elective percutaneous nephrolitotomy * American Society of Anesthesiologists (ASA) physical status I-II Exclusion Criteria: * Refusal to participate * Coagulopathy, * Infection at the block site * Allergy to local anaesthetics * Previous surgery in the block area * Severe systemic disease.

Locations (1)

Istanbul University, Istanbul Faculty of Medicine

Istanbul, Fatih, Turkey (Türkiye)

Outcomes

Primary Outcomes

Total 24-hour morphine consumption

Total 24-hour intravenous morphine consumption via patient controlled analgesia device

Time frame: 24 hours

Secondary Outcomes

Pain assessment

Pain assessment is evaluated using numeric rating scale (NRS 0-10; 0: no pain, 10: the worst pain imaginable)

Time frame: 24 hours

Additional analgesic requirement

If the Numeric Rating Scale (NRS) score exceeded 4, rescue analgesia consisted of additional morphine 0.02 mg/kg, plus intravenous paracetamol 1 g.

Time frame: 24 hours

Postoperative nausea and vomiting

Number of patients experienced postoperative nausea and vomiting .

Time frame: 24 hours

Patient satisfaction

Patient satisfaction is questioned using Likert scale:1-3 (1: dissatisfied, 2: neutral, 3: satisfied)

Time frame: Up to 24 hours

Surgeon satisfaction

Surgeon satisfaction is questioned using Likert scale:1-3 (1: dissatisfied, 2: neutral, 3: satisfied)

Time frame: Up to 24 hours

First rescue analgesic time

The first time patient required rescue analgesic

Time frame: 24 hours

Length of hospital stay

Time frame: Up to 1 week

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.