We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the incidence of postoperative acute kidney injury compared to propofol. The purpose is to provide practical evidence for perioperative management differentiated from other surgeries for hepatobiliary-pancreatic surgery patients for whom intraoperative fluid therapy is restricted.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
78
TCI of remimazolam (0.3 - 1.5 mcg/ml)
TCI of propofol (4.0 - 5.0 mg/mL)
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Acute kidney injury
serum creatinine
Time frame: preop, postop day 0, 1, 3, 5
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