The goal of this clinical trial is to learn if low-dose atropine eye drops work to reduce excessive watery eyes (epiphora) in adults. It will also learn about the safety of the eye drops. The main questions it aims to answer are: Do the eye drops reduce how often participants have watery eyes? What medical problems do participants have when taking the eye drops? Researchers will compare two strengths of the eye drops (0.005% and 0.01%) to see whether one works better than the other and whether the lower strength works as well as the higher one. Participants will: * Use the assigned eye drops in the affected eye(s) for one week * Visit the clinic twice for checkups and eye tests * Receive a follow-up phone call about two weeks after starting, to check on any symptoms
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
18
The interventions are two low doses of atropine ophthalmic solution
Greater Houston Eye Consultants
Houston, Texas, United States
North Texas Eye Specialists
Mesquite, Texas, United States
Munk Score Change
Proportion of subjects achieving a clinically meaningful Munk responder response (reduction of ≥2 Munk grades from baseline to Visit 2)
Time frame: Time Frame: From enrollment to the end of treatment at 1 week
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