Association Between 4D MRI Parameters and the Clinical Characteristics and Prognosis of Major Chronic Diseases

Overview

Cancer and cardiovascular diseases are among the leading causes of morbidity and mortality worldwide. Advanced imaging techniques such as 4D magnetic resonance imaging (MRI) enable quantitative assessment of hemodynamic and functional parameters beyond conventional imaging. The aim of this study is to evaluate the association between 4D MRI derived parameters and the occurrence, severity, and prognosis of major chronic diseases, and to explore their potential role as imaging biomarkers.

This is a single-center, prospective, observational registry study conducted at Ulsan University Hospital. The study will enroll 1,000 adult patients (≥ 19 years) undergoing cardiac MRI as part of routine clinical care in Korea. Participants will undergo an additional 4D MRI sequence during the same imaging session, which does not affect clinical decision-making or patient management. The primary objective of this study is to evaluate the association between quantitative imaging parameters derived from 4D MRI and the occurrence, severity, and prognosis of major chronic diseases.

Conditions

Eligibility