The primary goal for any oral implantologist is to obtain satisfactory healing and long-term treatment success. Osseointegration is the key to dental implant success8 and is required to achieve direct structural and functional connection between living bone and the surface of a load-bearing artificial implant, is critical for the long-term success of dental implants. Successful dental implant therapy relies on achieving proper osseointegration, which ensures a stable structural and functional bond between the implant surface and surrounding bone. Although dental implants show a high overall success rate of around 95%.
Implant success depends on several factors surgical and prosthetic factors (surgical technique and operator experience, timing and type of prosthetic loading and quality of pros-thetic rehabilitation), implant-related factors (material, design and surface), and patient-related factors (bone volume/quality at the recipient site and host response. Despite the high success rate of dental implants, which is reported to be around 95%, failures due to lack of osseointegration remain a significant challenge Implant failures are classified according to the timing of the loss to Early Dental Implant Failure (EDIF) or late dental implant failure (LDIF). Early implant failure occurs due to improper implant placement and restoration, low bone volume or density, systemic conditions, or smoking. Recent research has indicated that systemic health factors, particularly nutritional status, can significantly influence the process of osseointegration. Vitamin D is a major determinant of mineral homeostasis, promoting intestinal calcium and phosphorus absorption, which are required for optimal mineralization of bone. Vitamin D also exerts direct actions on bone (probably by regulating the expression of several bone growth factors). It controls mineral metabolism and the bone homeostasis by increasing calcium availability, by regulating PTH secretion, and by direct effects on bone formation and resorption.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
10
to address the relation between Vitamin D deficiency and Dental implant osseointegration for the identification of the participants whom may be non-responders to the vitamin D treatment
Future University in Egypt (FUE)
Cairo, New Cairo, Egypt
RECRUITINGTreatment of Dental Implant Osseointegration
Evaluation of the Primary implant stability measured immediately after implant placement using the Ostell device, which assesses resonance frequency analysis (RFA) values expressed as Implant Stability Quotient (ISQ). This measurement reflects the initial mechanical stability of the implant within the bone at the time of surgery.
Time frame: 3 Months
marginal bone loss after prosthesis placement
Marginal bone loss will be evaluated using cone beam computed tomography (CBCT) taken six months after prosthesis placement. The vertical distance between the implant shoulder and the first bone-to-implant contact will be measured on both mesial and distal aspects to assess the amount of peri-implant bone resorption over time.
Time frame: six months after proshtesis placement
Implant Survival Rate
Implant survival rate will be determined by the presence of the implant at the 6-month follow-up without any clinical or radiographic signs of failure, such as mobility, pain, infection, or significant bone loss. This outcome reflects the short-term success of the dental implant.
Time frame: six months after prosthesis placement
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