This is an open-label study being conducted in healthy adults, to learn what happens to the study medicine (camlipixant) they are receiving in a person's body over time (a pharmacokinetic \[PK\] study). The goal of the study is to understand how the body processes camlipixant, to check its safety and how well it is tolerated. Participants will receive camlipixant at different dose levels with different formulation types either on an empty stomach or after a meal.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Camlipixant will be administered.
GSK Investigational Site
Nottingham, Nottinghamshire, United Kingdom
Maximum Observed Concentration (Cmax) of Camlipixant
Time frame: Pre-dose and up to 48 hours post dose
Area Under the Curve from Zero up to 24 hours [AUC (0-24)] of Camlipixant
Time frame: Pre-dose and up to 24 hours post dose
Observed Concentration of Camlipixant at 24 hours (C24)
Time frame: 24 hours post dose
Number of Participants Experiencing Adverse Events (AEs)
Time frame: Up to 26 Weeks
Number of Participants Experiencing Serious Adverse Events (SAEs)
Time frame: Up to 26 Weeks
Number of Participants Experiencing Adverse Event of Special Interest (AESI)
Time frame: Up to 26 Weeks
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