Comparison of Green Tea, White Tea, and Chlorhexidine Oral Care for Prevention of Ventilator-Associated Pneumonia

Recep Tayyip Erdogan University63 enrolled

Overview

This study was conducted to compare the effects of oral care performed using chlorhexidine (CHX), green tea, and white tea solutions on oral health, functional status, and the development of ventilator-associated pneumonia (VAP) in intensive care unit patients receiving mechanical ventilation (MV)

This prospective controlled interventional study included 63 mechanically ventilated adult intensive care unit patients. Participants were assigned to one of three oral care groups receiving chlorhexidine (CHX), green tea, or white tea according to the study protocol. Oral health was assessed using the Bedside Oral Examination (BOE) guide on days 1, 3, and 7. The primary objective was to compare the incidence of ventilator-associated pneumonia (VAP) among the study groups. Secondary outcomes included changes in oral health status and functional oral assessment during follow-up.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Ventilation Acquired Pneumonia Mechanical Ventilation Oral Care

Interventions

Clorhexidine groupPROCEDURE

oral care using clorhexidine solution, green tea and white tea

Green Tea groupPROCEDURE

Participants received oral care using green tea according to the study protocol.

white tea groupPROCEDURE

Participants received oral care using white tea according to the study protocol.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Aged over 18 years 2. With no known allergies 3. Receiving invasive mechanical ventilator support 4. With a negative endotracheal aspirate culture on the day of ICU admission 5. Within the first 24 hours of mechanical ventilator support 6. Patients whose relatives agreed to participate in the study Exclusion Criteria: 1. Patients with positive endotracheal aspirate cultures within the first 48 hours of intensive care admission, 2. Patients undergoing radiotherapy or chemotherapy, 3. Patients with contraindications for oral care, 4. Patients with a platelet count below 30,000/mm³, 5. Patients who cannot be positioned appropriately, 6. Patients with agitation severe enough to prevent the procedure from being performed

Locations (1)

Recep Tayyip Erdogan University Research and Training Hospital

Rize, Merkez, Turkey (Türkiye)

Outcomes

Primary Outcomes

ventilator associated pneumonia devolopment

Comparison of the incidence of ventilator-associated pneumonia among the chlorhexidine, green tea, and white tea oral care groups.

Time frame: 7 days

Data from ClinicalTrials.gov

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