This retrospective observational study will use data from the OneOncology United States database to evaluate clinical outcomes in adults with relapsed/refractory multiple myeloma who received pomalidomide-containing or non-pomalidomide-containing treatment as second-line or third-line therapy after prior exposure to lenalidomide and a proteasome inhibitor.
Study Type
OBSERVATIONAL
Enrollment
341
Exposure to pomalidomide-containing index regimens, including daratumumab, pomalidomide, and dexamethasone (DPd) and carfilzomib, pomalidomide, and dexamethasone (KPd), administered in routine clinical practice.
Exposure to non-pomalidomide-containing index regimens, including daratumumab, lenalidomide, and dexamethasone (DRd), daratumumab, bortezomib, and dexamethasone (DVd), and daratumumab, carfilzomib, and dexamethasone (DKd), administered in routine clinical practice.
OneOncology Network
Nashville, Tennessee, United States
Progression-Free Survival (PFS) among participants who initiated pomalidomide-containing index regimens
Time frame: Up to 6 years
Overall Survival (OS) among participants who initiated pomalidomide-containing index regimens
Time frame: Up to 6 years
Overall Response Rate (ORR) among participants who initiated pomalidomide-containing index regimens
Time frame: Up to 6 years
Time to Next Treatment (TTNT) among participants who initiated pomalidomide-containing index regimens
TTNT is defined as the time from initiation of the pomalidomide-containing index regimen to initiation of the next subsequent line of therapy.
Time frame: Up to 6 years
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