Functional and Physiological Responses to Multicomponent Exercise in Older Adults

N/AActive Not RecruitingNCT07702227

Çanakkale Onsekiz Mart University40 enrolled

Overview

This study will examine functional and physiological responses to a 12-week multicomponent exercise program in community-dwelling older adults. Adults aged 60 to 81 years will be randomly assigned to either a multicomponent exercise group or a control group. The supervised exercise program will be performed twice weekly for 12 weeks and will include aerobic walking, resistance exercises, balance and agility training, flexibility exercises, and cool-down activities. Functional performance will be assessed using the six-minute walk test, the 30-second chair stand test, and the 8-Foot Up and Go test at baseline and after 12 weeks. Resting cardiac autonomic function will be assessed using heart rate variability. In addition, an exploratory responder-non-responder analysis will be conducted to examine whether baseline heart rate variability is associated with individual functional adaptations following the exercise program. This study may help identify physiological markers related to functional responsiveness to exercise in older adults.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Older Adults (60 - 85 Years Old)Aging Functional Capacity

Interventions

Multicomponent Exercise ProgramBEHAVIORAL

Participants in the exercise group will complete a supervised multicomponent exercise program twice weekly for 12 weeks. Each session will last approximately 45 to 50 minutes and include warm-up, aerobic interval walking, resistance exercises, balance and agility training, flexibility exercises, and cool-down activities. Exercise intensity will be monitored using the Borg Rating of Perceived Exertion scale and exercise difficulty will be progressively increased by increasing repetitions, walking duration, walking pace, and task complexity.

Eligibility

Sex: ALLMin age: 60 YearsMax age: 81 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * being 60 years of age or older, * being able to walk independently, * not having any serious cardiovascular, neurological, or musculoskeletal disease that would prevent exercise. * do not use medications that may affect autonomic nervous system function * Participants with controlled hypertension who were using stable routine medication were eligible, provided that the screening physician considered them medically suitable for exercise participation. Exclusion Criteria: * diagnosed cardiac arrhythmia, * uncontrolled hypertension, * use of medications that may affect autonomic nervous system function, * inability to perform functional performance tests. * Uncontrolled hypertension. Regular medication use was reviewed during medical screening. Participants were excluded when a medication or its adverse effects were considered to substantially compromise exercise safety, cardiac rhythm, or the ability to complete the exercise and assessment procedures.

Outcomes

Primary Outcomes

Change in six-minute walk distance

Functional walking capacity will be assessed using the six-minute walk test. The total distance walked in six minutes will be recorded in meters at baseline and after the 12-week intervention.

Time frame: Baseline and 12 weeks

Secondary Outcomes

Change in 30-second chair stand test performance

Lower-limb functional strength will be assessed using the 30-second chair stand test at baseline and after the 12-week intervention.

Time frame: Baseline and after 12 weeks

Change in 8-foot Up-and-Go test performance

Functional mobility and agility will be assessed using the 8-Foot Up-and-Go test at baseline and after the 12-week intervention.

Time frame: baseline and after 12 weeks