Research and Development of Reading Visual Aids for Low-Vision Individuals Based on Virtual Reality Technology

Beijing Tongren Hospital58 enrolled

Overview

Low vision substantially impairs reading ability and educational participation in adolescents. Existing assistive technologies, including optical magnifiers and electronic visual aids, are often limited by fragmented system architectures and insufficient support for multimodal cognitive processing. This study aimed to develop and evaluate a virtual reality (VR)-based intelligent reading aid integrating image enhancement, optical character recognition (OCR), text-to-speech (TTS), and large language model (LLM)-based semantic summarization for low-vision users.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Low Vision in Children

Interventions

VR-Based Intelligent Reading Aid

Intervention Description： Participants use the VR head-mounted intelligent reading aid to complete the same standardized reading tasks. The device integrates image enhancement, OCR, text-to-speech (TTS) and LLM-based semantic summarization. The test luminance is set at 400 nit (maximum recommended brightness). Each task contains 100 Chinese characters. Duration：Single session, approximately 5 minutes

Eligibility

Sex: ALLMin age: 9 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Safety Evaluation Cohort Inclusion Criteria： * Healthy adult volunteers aged 18-40 years * Best-corrected binocular visual acuity of 0.8 or better * Stereopsis of 60 arcsec or better * Tear film break-up time of at least 10 seconds,Horizontal phoria within 15 prism diopters at both distance and near,Spherical equivalent refractive errors between plano and -6.00 D,Astigmatism not exceeding 3.00 D,Anisometropia not exceeding 2.00 D * Intraocular pressure between 10 and 21 mmHg * All participants provided written informed consent before enrollment Exclusion Criteria: * Any current or previous organic ocular disease (such as keratitis, glaucoma, or retinal detachment) * Previous ophthalmic surgery (including refractive surgery or vitreoretinal surgery) * Systemic or psychiatric disorders that could affect study participation * Inability or unwillingness to complete the examination procedures Functional Evaluation Cohort: Inclusion Criteria: * Aged 9-17 years * Clinically diagnosed with visual impairment, meeting the inclusion criteria for low vision or severe visual impairment * Sufficient basic reading ability to complete the experimental tasks * Written informed consent obtained from all participants and their legal guardians prior to participation Exclusion Criteria: * Systemic or psychiatric disorders affecting participation * Inability or unwillingness to complete the examination procedures Functional Evaluation Cohort

Outcomes

Primary Outcomes

Change in Phoria

Variation of ocular phoria before and after single-session VR intelligent reading aid use, to evaluate the impact of near-eye VR optical system on adult eye position stability.