This study is to evaluate the safety, biodistribution, radiation dosimetry and tumor uptake of the \[68Ga\]/ \[131I\]-IR199 in patients with Claudin 18.2 positive gastric cancer and pancreatic cancer.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
10
\[68Ga\]/ \[131I\]-IR199, single dose
Huashan Hospital
Shanghai, China
RECRUITINGAbsorbed radiation dose (Gy) distribution in normal organs and tumors by quantitative SPECT/CT dosimetry
Absorbed radiation dose (Gy) distribution in normal organs and tumors by quantitative SPECT/CT dosimetry
Time frame: about 24 hours from time of injection, about 48 hours from time of injection and about 72 hours from time of injection
Safety Assessment
Incidence and severity of adverse events (AEs) as assessed by CTCAE v6.0
Time frame: From administration of [68Ga]/ [131I]-IR199 until 1 week after injection
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