Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients

N/ANot Yet RecruitingNCT07709247

Afyonkarahisar Health Sciences University50 enrolled

Overview

This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Osteoporosis Dental Caries Biomarkers Matrix Metalloproteinase 8

Eligibility

Sex: ALLMin age: 45 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Willing to give voluntary consent For Group 1, having been diagnosed with osteoporosis For Group 2, being systemically healthy and not having a diagnosis of osteoporosis/osteopenia Exclusion Criteria: * Having a chronic inflammatory or autoimmune disease Using glucocorticoids, anti-anxiety medications, antidepressants, or antiepileptic drugs Having been diagnosed with any malignancy Having any endocrine disease Having undergone periodontal treatment within the last 6 months

Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients

Overview

Conditions

Eligibility

Outcomes

Primary Outcomes

Central Contacts