So far, treatment with semaglutide (Wegovy) for therapy of obesity demonstrates substantial effects. However, most patients do not desire life-long pharmaceutical therapy or discontinue this treatment regime. This is accompanied by rapid weight regain. Moreover, numerous patients are open to an intermittent therapy. This trial aims to investigate whether two diet interventions can keep weight stable after weight loss with semaglutide in people with obesity or overweight.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
292
Dietary pattern, vegetarian version of the NutriAct pattern
Very low calorie diet as full meal replacement over 28 days in case of weight regain
weight in kg
Time frame: body weight in kg after weight loss (3 to 5 months) and dietary intervention (12 months)
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