Whey Protein and Adaptogenic Supplementation in Physically Active Males

Sports Performance and Applied Research in Trials and Analysis60 enrolled

Overview

The goal of this clinical trial is to learn whether whey protein, with or without an adaptogenic herb blend, can improve strength, recovery, stress, and wellbeing in active males. The adaptogenic blend contains 600mg ashwagandha root extract.The main questions the study aims to answer are: Does whey protein improve muscle strength and recovery in physically active males? Does adding ashwagandha to whey protein further improve stress, recovery, sleep, and wellbeing compared with protein alone? Are there differences between whey protein when combined with the adaptogenic blend? Researchers will compare two supplement groups: * Whey protein * Whey protein with ashwagandha Participants will: * Take their assigned supplement for 6 weeks * Attend two testing sessions before and after the intervention * Complete questionnaires about recovery, sleep, stress, soreness, and digestive health * Provide saliva samples to measure stress, hormone, immune, and inflammation markers * Complete muscle strength tests, including handgrip strength and push-up testing * Complete a 24-hour dietary recall * The study includes physically active males aged 18 to 45 years who regularly participate in structured training.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Sports Nutritional Sciences Sports Nutrition

Interventions

Whey proteinDIETARY_SUPPLEMENT

Participants will consume a whey protein supplement for 6 weeks. The supplement will be provided in identical blank tubs. Participants will be instructed to maintain their usual diet and training habits throughout the intervention period.

Dietary Supplement: Whey Protein With Adaptogenic BlendDIETARY_SUPPLEMENT

Participants will consume a whey protein supplement containing ashwagandha KSM-66® root extract (600 mg) for 6 weeks. Supplements will be provided in identical blank tubs. Participants will maintain usual diet and training habits during the study.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Male, aged 18-45 years * Currently participating in regular structured athletic or physical training (≥3 sessions per week) * Free from musculoskeletal injury that would prevent testing * Willing to maintain usual diet and training habits during the study * Not currently using protein supplements or adaptogenic supplements * Signing of informed consent form Exclusion Criteria: * Known allergy or sensitivity to dairy, ashwagandha or nightshades * Current use of prescribed medication that may interact with the supplements * Thyroid disorders, autoimmune conditions, hormone-sensitive conditions, or other medical conditions * Diagnosed eating disorder or condition affecting protein metabolism * Current musculoskeletal injury preventing participation in testing * Current use of other protein supplements or adaptogens * No signing of informed consent form

Outcomes

Primary Outcomes

Salivary Cortisol Concentration

Change in salivary cortisol concentration from baseline to post-intervention following 6 weeks of whey protein supplementation with or without an adaptogenic herb blend containing ashwagandha KSM-66®. Results will be reported in ng/mL.