18F-grazy-02 PET/CT of Granzyme B Expression for Monitoring Immunotherapy

Inclusion Criteria: 1. 18-75 years old; 2. ECOG score 0 or 1 point; 3. Participants with suspected or confirmed non-small cell lung cancer or melanoma who are suggested by the clinicians to conduct PET/CT imaging for tumor diagnosis or staging. Exclusion Criteria: 1. Pregnant or nursing; 2. Severe hepatic or renal dysfunction; 3. Low WBC (less than 3 x 10\^9/L); 4. Unable to comply with the PET/CT imaging procedures.