Establishing the Glycaemic Index of Vegetable Smoothies

University of Bath16 enrolled

Overview

Glycaemic responses to carbohydrates ingested as fruit and vegetables may vary depending on factors inherent to the fruit or vegetable, and on the type of sugar. The aim of this project is to investigate the glycaemic responses to two new fruit and vegetable smoothies, and to establish the glycaemic index for each product relative to a glucose reference. Participants will undertake 4 postprandial tests with 2 different test drinks following best practice guidelines for glycaemic index testing. The test drinks (GREEN and RED) will be matched for carbohydrate to the glucose reference (CONTROL) which will be sampled two times. Fingerstick capillary blood sampling will measure glucose concentrations. These data will provide insight into how differing formulations can alter the glycaemic responses to fruit and vegetable drinks.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Glycaemic Index Glycaemic Response Glycaemic Response Measurements

Interventions

Vegetable SmoothieOTHER

Commercially available fruit and vegetable smoothie

Vegetable SmoothieOTHER

Commercially available fruit and vegetable smoothie

Vegetable SmoothieOTHER

Commercially available fruit and vegetable smoothie

Vegetable SmoothieOTHER

Commercially available fruit and vegetable smoothie

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age: 18-65 years * Body mass index 18-30 kg/m2 Exclusion Criteria: * diagnosis of any form of diabetes * intolerances or allergies to any of the study procedures (e.g. fructose/inulin intolerance) * Fructose malabsorption * Inborn errors of fructose metabolism (e.g. fructokinase deficiency, aldolase B deficiency, fructose-1,6-bisphosphatase deficiency) * pregnant or lactating * any condition that could introduce bias to the study (e.g. diagnoses of lipid disorders, including cardiovascular disease, or therapies that alter lipid or glucose metabolism, such as statins or niacin).

Outcomes

Primary Outcomes

Glycaemic indices for 2 test drinks measured using capillary blood samples

Glycaemic indices \[2-hour incremental area under the glucose curve (mmol/L-1x120 minutes) for each of the 2 test drinks relative to mean value of control conditions (CONTROL, REPLICATE CONTROL), expressed as a percentage\] in capillary blood samples

Time frame: 120 minutes

Establishing the Glycaemic Index of Vegetable Smoothies

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes