Impact of Prophylactic Bone Radiation Therapy in Patients With Bone Metastases.

Inclusion Criteria: * Men or women, 18 years of age or older * Patients with solid cancer and bone metastases * Patients with bone lesions considered to be at intermediate risk for skeletal-related events (SINS score between 7 and 12, Mirels 8) or patients with lesions accompanied by Grade 1 epiduritis (Bilsky) * Enrolled in or covered by a social insurance program * Patients with an estimated life expectancy of more than 6 months Exclusion Criteria: * Hematologic disease * Patients with a lesion at high risk for skeletal-related events (SINS score of 13 or higher, MIRELS score of 9 or higher, or a multidisciplinary team (MDT) recommendation that surgery is necessary) * Patients with pain secondary to bone lesions requiring radiation therapy * Contraindication to radiation therapy due to a history of radiation therapy at the same site or a condition contraindicating radiation therapy * Pregnant or breastfeeding women * Contraindication to MRI in cases of spinal lesions; contrast-enhanced CT scan * Patients unable to understand the study for any reason or to comply with the trial requirements (language, psychological, geographic issues, etc.) * Patients under legal guardianship or conservatorship * Patients classified as WHO 3 or 4