Fucoidan(Seaweed) Based Gel Around Immediate Implants

Krishnadevaraya College of Dental Sciences & Hospital20 enrolled

Overview

The current study is a prospective randomised parallel mouth study to evaluate the effect of Fucoidan gel around immediate implant to assess the wound healing and bone regeneration in comparison to regular implant placement without any gel.

Twenty healthy individuals satisfying the inclusion and exclusion criteria were recruited for the study. A detailed, thorough medical and dental history was obtained and each patient was subjected to comprehensive clinical and radiological examination. All patients were informed about the nature of the study, procedure involved, potential benefits and risks associated with procedure and written informed consent were obtained from all patients. All the patients underwent scaling and root planning. Following randomization, the site will be assigned to one of the two study groups. 1. test group(immediate implant+ fucoidan gel) 2. control group (only immediate implant without any gel)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Wound Healing Bone Regeneration

Interventions

Fucoidan extracted from F. VesiculosusDRUG

patients with immediate implant with Fucoidan gel coating prior to implant placement

immediate implant placementPROCEDURE

patients with immediate implant without any implant surface coating prior to implant placement

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients at least above 18 years of age. 2. Patients presenting with Stage I/II and Grade B periodontitis. 3. Class I extraction socket defects according to modified Elian et al 2021. 4. The recipient sites of the implant will be free from pathological conditions. 5. Patients who will comply with oral health care instructions and necessary visits 6. Cases undergoing extraction for dental caries or endodontic conditions. Exclusion Criteria: 1. Uncontrolled diabetes and severe cardiovascular or infectious diseases 2. Patients with Intravenous and oral bisphosphonate therapy. 3. Patients who are unwilling to return for the follow-up examination. 4. Smokers, lactating and pregnant women. 5. Patients who are psychologically unable to participate. 6. Patients with poor oral hygiene.

Locations (1)

Krishnadevaraya college of dental sciences and hospital

Bangalore, Karnataka, India

Outcomes

Primary Outcomes

wound healing index after immediate implant placement

Landry, Turnbull and Howley wound healing index

Time frame: 7th day,14th day, 21st day, 1month, 3months and 6 months

Secondary Outcomes

crestal bone level

using RVG with 1 mm grid

Time frame: baseline, 3month and 6 month

gingival tissue thickness

Time frame: baseline , 3months and 6 months

keratinised tissue width

Time frame: baseline,3months and 6 months

CBCT : linear measurement

Time frame: baseline and 6months

Plaque Index

Time frame: 3months

Gingival Index

Time frame: 3months

Modified sulcular bleeding index

Time frame: 3 months

Probing depth (PD)

Time frame: 1month,3month and 6 month

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.