Children with severe-to-profound congenital hearing loss often experience significant language development challenges. While cochlear implants (CIs) can restore auditory input, outcomes vary widely, even among those who receive implants early (before age 2) and undergo consistent speech therapy. This study aims to identify neural mechanisms underlying these differences.
Study Type
OBSERVATIONAL
Enrollment
150
The beta coefficient of theta-gamma phase-amplitude coupling (PAC) in the linear mixed-effect model
language composite score is the dependent variable
Time frame: at enrollment
Power-spectrum density (PSD) of the EEG resting-state oscillations
Time frame: at enrollment
peak frequencies of the EEG resting-state oscillations
Time frame: at enrollment
Multivariate temporal response functions (mTRF) in audiovisual and audio conditions
Time frame: at enrollment
Comparison of the 40Hz Auditory steady-state responses (ASSR) between participants with or without GJB2 variant
Time frame: at enrollment
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