The purpose of this clinical study is to look at how well a study medicine called cagrilintide helps people living with excess body weight to lose weight. Participants will either get cagrilintide, the active study medicine being tested or placebo, a medicine that has no active medicine in it. Which treatment participants get is decided by chance. Cagrilintide is a new medicine under development that doctors cannot prescribe yet, but it has been tested in humans before. Participants will be in this clinical study for about 9 months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
285
Cagrilintide will be administered subcutaneously.
Placebo matched to cagrilintide will be administered subcutaneously.
Placebo matched to semaglutide will be administered subcutaneously.
Hope Clin Res & Wellness
Conyers, Georgia, United States
RECRUITINGEast West Med Res Inst
Honolulu, Hawaii, United States
RECRUITINGWalgreens - Store 11760
Oak Park, Illinois, United States
NOT_YET_RECRUITINGMidwest Inst For Clin Res
Indianapolis, Indiana, United States
Relative change in body weight
Measured as percentage (%).
Time frame: From baseline (week 0) to end of treatment (week 26)
Number of Treatment Emergent Adverse Events (TEAEs)
Measured as count of events.
Time frame: From baseline (week 0) to end of study (week 33)
Number of Treatment Emergent Serious Adverse Events (TESAEs)
Measured as count of events.
Time frame: From baseline (week 0) to end of study (week 33)
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The Alliance for Multispecialty Research LLC AMR
Lexington, Kentucky, United States
RECRUITINGPharmQuest
Greensboro, North Carolina, United States
RECRUITINGKDCILM, LLC & Accellacare US, Inc.
Wilmington, North Carolina, United States
RECRUITINGCoastal Carolina Res Ctr
North Charleston, South Carolina, United States
RECRUITINGHealth Res of Hampton Roads
Newport News, Virginia, United States
RECRUITINGNational Clin Res Inc.
Richmond, Virginia, United States
RECRUITING...and 26 more locations