Postoperative Pain After Dexamethasone Injection by Two Techniques in Irreversible Pulpitis

Ain Shams University66 enrolled

Overview

The aim of this randomized clinical trial to evaluate the effect of dexamethasone in two different techniques on postoperative pain by dividing patients randomly into three groups: * Group I: buccinator injection of dexamethasone. * Group II: buccal infiltration of dexamethasone. * Group III (Control): IANB using local anesthesia only post operative pain will be evaluated subjectively by patients by VAS score after procedure immediately and follow up for 12, 24 and 72 hours and frequency of analgesic intake

the previous studies used dexamethasone with LA to prolong the duration of nerve block , Dexamethasone is used in reducing intraoperative endodontic pain the study main aim is to overcome the problem of severe postoperative pain after endodontic treatment in patients with acute irreversible pulpitis by evaluating the effect of dexamethasone in two different techniques by giving dexamethasone injection of buccinator muscle, or dexamethasone as buccal infiltration, and comparing the results with inferior alveolar nerve block using local anesthesia only. pain score evaluated using VAS score preoperatively and postoperatively with different anesthetic techniques after endodontic treatment.and their effet on frequency of analgesic intake

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Post Operative Pain, Acute

Interventions

dexamethasone 8mgDRUG

8mg/2ml injected slowly 30 sec for 1ml as single injection before the endo treatment

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Both genders * Older than age of (18 to 60) years * Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study * Having a mandibular molar tooth with vital pulp * These patients were also suffering from symptomatic irreversible pulpitis ,intermittent or continuous sharp pain that lasts longer after removal of the stimulus * Patients with moderate to severe symptoms VAS≥4 Exclusion Criteria: * Vulnerable group; pregnant females, mentally ill and diseased patientsetc.… * Patients irritable to local anesthesia * Patients who are supposed to take plain anesthesia * Use of analgesic or antibiotic within 6 hours before the visit * Absence of bleeding in the pulp chamber during cavity preparation * Severe periodontal disease b- Patients' randomization, allocation and blinding:

Locations (1)

Faculty of Dentistry Ain Shams University

Cairo, Egypt

Outcomes

Primary Outcomes

visual analogue score (VAS) from 0 to 10

VAS preoperative ,immediately postoperative,12hrs,24hrs,72hrs

Time frame: postoperative 72 hours

Data from ClinicalTrials.gov

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