An Evaluation of Long-Term Supplement Use on Biological Age and Metabolic Health Markers - The BioAge Trial

Shaklee Corporation300 enrolled

Overview

This study will evaluate whether dietary supplement use (\> 1 year) is associated with differences in biological age relative to chronological age, as well as differences in metabolic health and functional fitness tests.

Using a cross-sectional study design, information will be obtained by biomarker analysis, questionnaires, physical examination, and physical function from a convenience sample of long-term users of dietary supplements. Comparison data for non-users and single multivitamin/mineral and multiple supplement users will be obtained from the National Health and Nutrition Examination Survey (NHANES).

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Generally Healthy Adults Who Are Long-term Supplement Users

Interventions

No Intervention: Observational CohortOTHER

No intervention: observational cohort

Eligibility

Sex: ALLMin age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adults aged 40 years or older. * Verified long-term Sponsor supplement use (\>1 year). * Willing and able to provide informed consent and comply with study procedures. * Able to fast overnight (\>8 hours) prior to the study visit. * Willing and able to travel to the test site. * Ambulatory and currently free of injury or other physical impairment that hinders mobility. * Willing to use a personal smart phone or computer with internet access and active email address. * Willing to adhere to all study procedures and sign forms providing informed consent to participate in the study and authorization to release relevant protected health information. Exclusion Criteria: * Current or recent (within 6 months) diagnosis of cancer except for non-melanoma skin cancer. * Participant is pregnant or lactating. * Participant has a pacemaker or other implanted electronic device. * Any condition the study staff believes would interfere with the participant's ability to provide informed consent or comply with the study protocol, which might confound the interpretation of the study results or put the person at undue risk.

Locations (1)

Biofortis Clinical Research

Addison, Illinois, United States

RECRUITING

Outcomes

Primary Outcomes

Difference between biological and chronological age (years) calculated using a validated biological age calculator

Differences will be compared to an NHANES cohort, where possible.