High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)

N/ANot Yet RecruitingNCT07760727

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital120 enrolled

Overview

This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Participants will be assigned to receive either high-flow nasal oxygen therapy or conventional oxygen therapy during the procedure. The incidence of respiratory complications, blood gas changes, and recovery outcomes will be compared between the two groups.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

High Flow Oxygen Therapy ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION Sedation Sedation Complication Blood Gas Analysis

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Age ≥18 years. Scheduled to undergo sedated EBUS-TBNA. Ability to provide written informed consent. ASA physical status I-III. Exclusion Criteria: * Age \<18 years. * Pregnancy. * Requirement for endotracheal intubation or general anesthesia. * Severe hemodynamic instability. * Refusal to participate in the study. * Contraindication to high-flow nasal oxygen therapy.

Outcomes

Primary Outcomes

Respiratory Complications

Incidence of respiratory complications during sedated EBUS-TBNA, including hypoxemia, oxygen desaturation, apnea, airway obstruction, and the need for airway interventions.

Time frame: During the procedure

Secondary Outcomes

Oxygen partial pressure (PaO2)

Changes in venous oxygen partial pressure(PaO2) measured at baseline and after sedated EBUS-TBNA

Time frame: Baseline and within 15 minutes after completion of the endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) procedure

Carbon dioxide partial pressure (PvCO2)

Changes in venous carbon dioxide partial pressure (PvCO2) measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA.

Time frame: Baseline and within 15 minutes after completion of the EBUS-TBNA

Venous pH

Changes in venous pH measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA

Time frame: Baseline and within 15 minutes after completion of the EBUS-TBNA procedure.

Venous Oxygen Saturation (SvO2)

Changes in venous oxygen saturation (SvO2) measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA.

Time frame: Baseline and within 15 minutes after completion of the EBUS-TBNA procedure.

Recovry Time

Time from completion of sedated EBUS-TBNA until achievement of a Modified ALdrete Recovery Score ≥9.

Time frame: Up to 2 hours post-procedure

Central Contacts

ÖZLEM KAPUSUZ KÖRDUMAN, MD

CONTACT

+905058002027 zlmkpsz@hotmail.com

Güldeniz Argun, Prof