Study of Cognitive-Linguistic Profiles: The Role of Executive Control in Aphasia

N/ANot Yet RecruitingNCT07766356

University Hospital, Toulouse30 enrolled

Overview

In France, stroke affects 150,000 people annually and is the leading cause of acquired disability in adults; 10-12% of patients exhibit mild post-stroke aphasia, a condition defined by language difficulties. Few studies describe mild post-stroke aphasia, and none characterize the impairment of linguistic executive control in this population; consequently, its prevalence remains unknown. To date, the role of linguistic executive control in mild aphasia remains an open question. The aim of this project is to investigate linguistic executive control impairment in stroke survivors with mild aphasia, provide an initial estimate of its prevalence, and demonstrate its interactions with other linguistic and communicative aspects, as well as with executive and attentional functions.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Stroke

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient who has experienced a first ischemic stroke resulting in clinical symptoms within the last 3 months and is receiving care in the Physical Medicine and Rehabilitation department. * Score ≤ 31 on the conversational speech observation scale of the MEC test (Montreal Protocol for the Evaluation of Communication). * Patients with a BDAE score ≥ 3 (Boston Diagnostic Aphasia Examination - French version, Mazaux J.-M. \[1990\]); this score is the gold standard in aphasiology. * Native French-speaking patient capable of understanding oral or written instructions. Exclusion Criteria: * Patients exhibiting behavior or a clinical condition incompatible with test administration, as assessed by the clinician. * Known major visual, auditory, or motor impairments incompatible with test performance. * Known neurodegenerative and/or neurodevelopmental disorders. * Known social cognition disorders (e.g., ASD).

Outcomes

Primary Outcomes

measure the proportion of patients with mild post-stroke aphasia exhibiting deficits in linguistic executive control within three months of a first stroke

CATEX score result (deficit score if below the mean value minus 1.65 times the standard deviation)