Evaluation of Non-Surgical Treatment of Breast Abscess

Sohag University50 enrolled

Overview

Breast abscess is a localized suppurative complication of breast infection commonly managed by ultrasound-guided needle aspiration combined with antibiotic therapy. This prospective observational study aims to evaluate the clinical outcomes and prognostic factors associated with successful non-surgical management versus treatment failure requiring surgical intervention in adult female patients with lactational and non-lactational breast abscesses.

Breast abscess represents a severe complication of mastitis encountered in lactating and non-lactating women. While traditional management relied on incision and drainage, modern approaches emphasize minimally invasive non-surgical treatment using ultrasound-guided needle aspiration combined with appropriate antibiotics to minimize morbidity, accelerate healing, avoid fistula formation, and preserve breastfeeding. This prospective observational study will be conducted at the Department of General Surgery, Sohag University Hospitals. Eligible female patients presenting with lactational or non-lactational breast abscesses will undergo initial non-surgical treatment with ultrasound-guided needle aspiration/re-aspiration with or without catheter drainage plus culture-guided antibiotic therapy. Patients will be followed up clinically and sonographically for 4 weeks to evaluate treatment success, time to resolution, complication rates, and predictors associated with treatment failure requiring surgical intervention.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Breast Abscess

Interventions

Ultrasound-guided needle aspiration and antibioticsPROCEDURE

Ultrasound-guided needle aspiration of the abscess cavity (repeated every 2-3 days if residual collection persists) with or without catheter drainage, combined with systemic empirical and culture-sensitive antibiotic therapy.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult female patients diagnosed with lactational and non-lactational breast abscesses on clinical and sonographic grounds. * Patients undergoing initial non-surgical treatment in the form of ultrasound-guided aspiration/re-aspiration with or without catheter drainage plus systemic antibiotics. Exclusion Criteria: * Suspicion of inflammatory breast cancer or underlying breast malignancy. * Frank skin necrosis, thinning, or ruptured abscess overlying the affected breast. * Patients with breast implants in situ on the affected side. * History of breast surgery within 90 days of presentation. * Chronic or recurrent breast abscesses.

Locations (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Outcomes

Primary Outcomes

Successful Non-Surgical Management Rate

Complete clinical and sonographic resolution of the breast abscess without the necessity of formal surgical incision and drainage during the index episode.

Time frame: Up to 4 weeks post-treatment

Secondary Outcomes

Time to Complete Resolution

Duration in days required from initiation of treatment until complete clinical and ultrasonographic resolution.

Time frame: Up to 4 weeks

Number of Aspiration Sessions

Total number of ultrasound-guided needle aspiration sessions performed to achieve complete resolution.

Time frame: Up to 4 weeks

Rate of Treatment Failure Requiring Surgical Intervention

Percentage of patients who failed non-surgical management and required formal surgical incision and drainage.

Time frame: Up to 4 weeks

Rate of Procedure-Related Complications

Incidence of complications related to treatment such as skin necrosis, breast fistula formation, and galactocele.

Time frame: Up to 4 weeks

Data from ClinicalTrials.gov

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