The primary goal of this single centre observational study is to look at factors that affect serum bicarbonate levels in patients on maintenance dialysis. This will be done by collecting demographic information, relevant medical history, dialysis history, potential renal acid load from diet by recording different foods consumed over 2 days in a food diary and bicarbonate levels at 3 intervals, pre and post dialysis session 1 and pre dialysis session 2. Bicarbonate levels are of significant interest as an indicator of metabolic acidosis in CKD dialysis patients. This study will allow us to understand the efficacy of different dialysis modalities in controlling bicarbonate levels. It will also enable us to understand the idea of individualizing dialysis for patients in terms of not using a standard concentration of dialysate for all patient undergoing dialysis in this center.
Cross sectional study
Study Type
OBSERVATIONAL
Enrollment
100
East and North Hertfordshire NHS Trust
Stevenage, Hertfordshire, United Kingdom
RECRUITINGChange in serum bicarbonate levels in patients on haemodialysis
Serum bicarbonate concentration measured across two dialysis sessions (HD1 and HD2) measured as Pre HD1, Post HD2 and Pre HD2.
Time frame: 3 months
Dietary Acid Load
Potential renal acid load
Time frame: ~ 3 months
Volume of Haemodiafiltration
Haemodiafiltration volume delivered
Time frame: 3 months
Indicators of dialysis dose
Pre HD1 and Post HD1 serum urea
Time frame: 3 months
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