The Relationship Between Lipedema and Osteoporosis

N/ANot Yet RecruitingNCT07779603

Fatih Sultan Mehmet Training and Research Hospital120 enrolled

Overview

The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.

Clinical characteristics such as age, body mass index (BMI), education level, marital status, age at menopause, number of births, duration of illness, occupation, duration of lactation, history of fractures, family history of fractures, smoking, alcohol consumption, dairy product intake, sun exposure habits, stage of lipedema, and type of lipedema will be recorded. Your blood test results obtained prior to routine osteoporosis treatment (complete blood count, erythrocyte sedimentation rate, C-reactive protein, calcium, phosphorus, alkaline phosphatase (ALP), parathyroid hormone (PTH), and 25-hydroxyvitamin D levels) will be recorded. The severity of lower extremity pain will be assessed using the Visual Analog Scale (VAS). Scores on the lower extremity functional scale will be recorded. For patients with lipedema, the average and most severe lower extremity pain experienced over the past month will be recorded. Dual-energy X-ray absorptiometry (DEXA) measurements assessing current bone loss will be recorded for the lumbar and hip regions.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Lipedema Osteoporosis

Interventions

DXAOTHER

Dual-energy X-ray absorptiometry (DXA) measurements will be recorded for the lumbar and hip regions

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * being literate * voluntarily agreeing to participate in the study * being a postmenopausal woman * having a diagnosis of lipedema Exclusion Criteria: * the presence of other types of edema in which a component other than lipedema predominates (e.g., lymphedema, venous edema, edema associated with heart or kidney failure, etc.) * chronic liver disease, * body mass index (BMI) of over 50.0 (this condition reflects severe obesity, which has a significant impact on health beyond lipedema alone) * the presence of rheumatological diseases that may lead to secondary osteoporosis * a history of cancer, endocrine disorders, neurological disorders, certain gastrointestinal disorders * use of medications related to osteoporosis * being under 18 years of age

Outcomes

Primary Outcomes

DXA

Dual-energy X-ray absorptiometry (DEXA) measurements for the lumbar and hip regions for the lumbar and hip regions

Time frame: 1 day

Data from ClinicalTrials.gov

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