This study aims to compare the effects of RO7568282 versus a placebo in people in the early stages of Alzheimer's disease (AD).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
450
Change From Baseline to Week 72 in Clinical Dementia Rating, Sum of Boxes (CDR-SB)
Time frame: From baseline up to Week 72
Change From Baseline Through Week 72 in Alzheimer's Disease Assessment Scale-Cognition 13 (ADAS-Cog-13)
Time frame: From baseline up to Week 72
Change From Baseline Through Week 72 in Alzheimer's Disease Cooperative Study - Activities of Daily Living Inventory (ADCS-ADL) Total Score and Instrumental Score
Time frame: From baseline up to Week 72
Incidence of Adverse Events (AEs)
Time frame: Up to approximately Week 76
Change From Baseline in Columbia-suicide Severity Rating Scale (C-SSRS)
Time frame: From baseline up to Week 76
Plasma Concentrations of RO7568282 and its Metabolite[s]
Time frame: Up to approximately Week 76
Reference Study ID Number: BP46554 https://forpatients.roche.com/ No attachments to email below.
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