Efficacy of Mixture of Vancomycin With Xenograft for Immediate Implant Placement in Chronic Infected Socket

Overview

Adding local vancomycin to xenografts greatly benefits stability, bone density, and limits marginal bone loss in dental implants in infected socket.

Aim: to evaluate how adding vancomycin to the xenograft in the infected socket affects bone preservation during immediate implant placement. Background: Proper dental implant placement is crucial for successful osseointegration, as the resultant tiny gaps between the implant and bone can affect implant stability. These gaps are better filled with xenografts, which are easy to handle, widely available, and provide an osteoconductive framework that supports better implant outcomes. It's also important to prevent nearby infections, since the infected socket can damage both soft and hard tissues, raising the risk of peri-implantitis and further implant failure. Applying locally delivered antibiotics during placement can help protect and manage against early infections. Patients and methods: Twenty patients with mandibular extraction sockets participated in the study divided into two groups: 10 patients received a xenograft mixed with vancomycin (Group I), and 10 patients received a xenograft alone (Group II). Implant stability was assessed clinically at baseline and at 6 months only, while CBCT scans were used to monitor crestal bone loss and bone density at baseline, 6 months, and 9 months. Post-surgical complications were also monitored throughout the study period.

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Eligibility

Locations (1)

Outcomes