AI-Powered Hepatitis C Single-Encounter Test-and-Treat

Inclusion Criteria: * Age 22-65 years old, presenting to the Emergency Department (ED) who are undergoing antibody testing as part of universal screening * Patients to be discharged from the ED or ED Observational units Exclusion Criteria: * Capacity to Consent * Emergency Severity Index (ESI) Level one (high acuity patients) * Known noninvasive serologic tests above proprietary cutoffs indicating cirrhosis (example - FibroSure, Enhanced Liver Fibrosis Test, etc.) * Known clinical evidence of cirrhosis (egliver nodularity and/or splenomegaly on imaging, platelet count \<150,000/m3, etc.) * Known prior liver biopsy showing cirrhosis •Pregnancy * Known or suspected Hepatocellular carcinoma * Followed by hospice or transplant, have a life expectancy \< 1 year * Chronic Kidney Disease (CKD) or on dialysis * Allergy to study medications * Patients admitted to the hospital