This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia. Eligible participants will receive either magnesium sulfate or lidocaine before endotracheal intubation. Heart rate and blood pressure will be recorded at predefined time points before and after intubation to compare the effectiveness of the two interventions in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
78
intravenous magnesium Sulphate 30mg /kg diluted in 100ml normal saline, administered 90 sec before induction of general anesthesia
heart rate 5minutes after endotracheal intubation
Time frame: 5 minutes after endotracheal intubation
systolic blood pressure 5 minutes after endo tracheal intubation
Time frame: 5 minutes after endotracheal intubation
mean arterial pressure 5 minutes after endotracheal intubation
Time frame: 5 minutes after endotracheal intubation
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