Preoperative Anaemia and Early Postoperative Complications After Major Gastrointestinal Surgery

University of Ioannina146 enrolled

Overview

This prospective observational cohort study evaluated the association between preoperative anaemia and early postoperative morbidity in adults undergoing major gastrointestinal surgery at the University Hospital of Ioannina, Greece. Consecutive patients undergoing elective or urgent open or laparoscopic gastrointestinal surgery were enrolled. Preoperative anaemia was defined as haemoglobin \<13.0 g/dL in men and \<12.0 g/dL in non-pregnant women. Patients were followed from surgery until hospital discharge or postoperative day 8, whichever occurred first. The primary outcome was any postoperative complication during this period. Secondary outcomes were major postoperative complications, defined as Clavien-Dindo grade III or higher, and discharge beyond the expected recovery period. The study also evaluated whether the association between preoperative anaemia and postoperative morbidity persisted after accounting for comorbidity, urgency of surgery, and surgical risk.

Study Type

OBSERVATIONAL

Enrollment

146

Conditions

Anemia Postoperative Complications

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \>18 years * Ability to provide written informed consent * Undergoing major abdominal gastrointestinal surgery during the study period * Elective or urgent surgery * Open or laparoscopic surgical approach Exclusion Criteria: * Emergency surgery * Organ transplantation

Locations (1)

Outcomes

Primary Outcomes

Any Early Postoperative Complication

Occurrence of at least one postoperative complication recorded prospectively using a predefined list. Postoperative complications were graded according to the Clavien-Dindo classification.

Time frame: From the day of surgery through postoperative day 8 or until earlier hospital discharge

Secondary Outcomes

Major Postoperative Complication

Occurrence of at least one postoperative complication classified as Clavien-Dindo grade III or higher.

Time frame: From the day of surgery through postoperative day 8 or until earlier hospital discharge

Number of Participants Remaining Hospitalized Beyond Postoperative Day 8

Number of participants whose hospital stay extended beyond postoperative day 8, determined from the recorded hospital discharge date. Participants discharged on or before postoperative day 8 were not considered to have this outcome.

Time frame: Postoperative day 8