Objective: To compare efficacy of topical tranexamic acid versus standard postop care in reducing wound drainage following modified radical mastectomy (MRM). Study Design: Randomized controlled trial. Setting and Duration: Department of General Surgery, Gulab Devi Hospital, over period of six months. Methods: Total of 60 patients undergoing MRM were enrolled and randomly allocated into two groups, with 30 patients in each group. Group I received topical tranexamic acid applied to surgical wound, while Group II received standard postop care without tranexamic acid. Objective was to assess total wound drainage ( in ml), duration of drainage (in days) and frequency of wound infection among two group. Data were analyzed using SPSS version 26, and p-value ≤0.05 was considered statistically significant.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
TRANEXAMIC acid topical application
Gulab Devi Educational
Lahore, Punjab Province, Pakistan
Gulab Devi hospital
Lahore, Punjab Province, Pakistan
Wound drainage
To compare efficacy of topical application of tranexamic acid compared to standard postoperative care after MRM in terms of duration of wound drainage
Time frame: 6 months
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