Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection

University of Chicago140 enrolled

Overview

The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee. Participants will: 1. Be randomly divided into getting their steroid injection on the inside or outside of their knee. 2. Answer a pain survey before their injection as well as over the phone 2 weeks, 6 weeks, and 12 weeks after their injection.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

140

Conditions

Osteoarthitis Osteoarthritic Knee Pain Osteoarthritis (OA)Osteoarthritis (OA) of the Knee Osteoarthritis in the Knee

Interventions

Anteromedial InjectionPROCEDURE

If randomized to this intervention, patients will receive a corticosteroid injection in the anteromedial side of their knee.

Anterolateral InjectionPROCEDURE

If randomized to this intervention, patients will receive a corticosteroid injection on the anterolateral side of their knee.

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 40 * Clinical diagnosis of knee OA with predominant medial compartment symptoms * Radiographic moderate-to-severe medial compartment OA (KL grade 3-4 or equivalent) * Agreed to and preparing to receive a CSI of the knee as part of standard care from surgeon, regardless of past injection of the knee * Able to provide informed consent * Able to complete phone, email, or MyChart follow-ups in English Exclusion Criteria: * Predominant lateral compartment OA or patellofemoral-only OA * Inflammatory arthritis (RA, gout flare, etc.) * Suspected or confirmed joint infection or overlying cellulitis * Prior knee arthroplasty on the index knee * Planned surgery for index knee within 12-week follow-up * Inability to complete follow-up assessments * Other clinician-determined contraindication to CSI

Locations (5)

Bolingbrook Clinic

Bolingbrook, Illinois, United States

RECRUITING

Hyde Park Clinic

Chicago, Illinois, United States

RECRUITING

La Grange Clinic

La Grange, Illinois, United States

RECRUITING

Orland Park Clinic

Orland Park, Illinois, United States

RECRUITING

Woodridge Clinic

Woodridge, Illinois, United States

RECRUITING

Outcomes

Primary Outcomes

Numeric Pain Rating Scale

This survey asks patients to rate their pain on a scale from 0 to 10.

Time frame: Pre-procedure, 2 weeks, 6 weeks, and 12 weeks post-injection

Knee Osteoarthritis and Outcome Score-Joint Replacement

This standardized survey asks patients to describe the impact of their knee stiffness and pain on daily tasks.

Time frame: Pre-procedure, 2 weeks, 6 weeks, and 12 weeks post-injection

Secondary Outcomes

Institutional Survey on Satisfaction with Injection

This survey asks patients to rate their satisfaction with their corticosteroid injection on a scale from 0 to 10.

Time frame: 2 weeks, 6 weeks, and 12 weeks post-injection

Patient Global Impression of Change

This survey asks patients to rate their overall health status on a scale from 1 to 7.

Time frame: 2 weeks, 6 weeks, and 12 weeks post-injection

Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection

Overview

Conditions

Interventions

Eligibility

Locations (5)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts