This prospective, multicenter, single-arm phase II clinical trial is designed to enroll patients with spinal metastases classified as Bilsky grade 1c-3 who will receive stereotactic body radiation therapy (SBRT). The objective of this study is to assess the efficacy and safety of SBRT in the treatment of spinal metastases with epidural spinal cord compression (Bilsky grade 1c-3).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
50
SBRT treatment for patients with spinal cord metastasis and epidural spinal cord compression (Bilsky grade 1c-3). All patients will be treated using the CyberKnife system and treated once daily within 1-2 weeks.
Tianjin Medical University Cancer Institute and Hospital
Tianjin, China
RECRUITINGLocal failure
defined as radiographic and/or clinical progression within the radiotherapy target volume.
Time frame: The time from randomization to local failure assessed up to 12 months
OS
defined as the time from randomization (or study entry) to death from any cause.
Time frame: the time from randomization to death from any cause assessed up to 12 months
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