Wrist Nerve Block as a New Treatment in Patients With Rheumatoid Arthritis

N/ANot Yet RecruitingNCT07814989

Sohag University180 enrolled

Overview

Rheumatoid arthritis is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.\[1\]

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

180

Conditions

Rhematoid Arthritis

Interventions

Wrist local steroid injectionPROCEDURE

Wrist nerve block by injection is a diagnostic or therapeutic procedure used to treat chronic wrist pain, typically arising from arthritis or instability, by interrupting sensory nerve signals (mainly PIN/AIN nerves) with an anesthetic or neurolytic agent. This less-invasive approach provides pain relief, often serving as a predictor for success before permanent surgical denervation.\[4\]

Eligibility

Sex: ALLMin age: 16 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.\[8\] 2. Oligoarticular RA patients including wrist joint. 3. Age above 18 years old. 4. Patient cooperative and can answer questions. Exclusion Criteria: 1. Other rheumatologic or collagen diseases. 2. Age below 18 years. 3. Patients who underwent concomitant procedures to address underlying pathology such as radial styloidectomy, ulna shortening, fracture fixation, arthroplasty, arthrodesis, and ligament reconstructions. 4. Patients who suffered from hand deformities or limitation. 5. Uncooperative patients.

Locations (1)

Sohag University Hospital

Sohag, Egypt

Outcomes

Primary Outcomes

Change in wrist pain severity measured by the Visual Analogue Scale (VAS) from baseline to Week 16

Change in wrist pain severity measured using the Visual Analogue Scale (VAS) from baseline to Week 16 Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Wrist pain severity will be assessed using the Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 represents no pain and 10 represents the worst imaginable pain. Higher scores indicate greater pain. The change in VAS score from baseline to Week 16 will be assessed.

Time frame: Baseline to Week 16

Assessment of wrist pain improvement

• Change in wrist pain severity measured by the Visual Analogue Scale (VAS) from baseline to Week 16

Time frame: 16 weeks

Central Contacts

Youssra Ali Resident

CONTACT

00201122040682 youssralam3ie@gmail.com

Ahmed mahrous elsamman

CONTACT

00201122040682

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.