Aerobic Exercise as an Adjunct Therapy for Depression

N/ARecruitingNCT07819448

Manahil Gill66 enrolled

Overview

The goal of this study is to compare the reduction in the severity of depression after a duration of 06 weeks between patients receiving conventional therapy (antidepressant; Sertraline) only and those receiving both conventional therapy and a structured aerobic exercise (cycling, brisk walking).

This study will compare two groups A and B for 06 weeks to study the reduction in severity of depression. * Comparison group (Group-A): In this group participants will receive standard antidepressant treatment such as Sertraline (SSRIs) and psychotherapy (CBT) only. After 06 weeks, patients will again be assessed for their level of depression using the BDI scale. * Experimental group (Group-B): In this group participants will undergo structured exercise program in addition to conventional pharmacotherapy and psychotherapy. They will be introduced to aerobic exercises which includes cycling and brisk walking and will undergo three supervised sessions for 35 minutes each, per week for total 06 weeks under supervision of trainee psychiatry.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Depressive Disorder

Interventions

Structured Aerobic exerciseBEHAVIORAL

Participants will receive structured, supervised aerobic exercise ( cycling, brisk walking), in addition to conventional treatment consisting of 03 sessions per week, 35 minutes each for 06 weeks.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: i. All new patients diagnosed with moderate and severe depression using BDI scale according to ICD-11 criteria between the ages of 18-55 years. ii. Both genders will be included. Exclusion Criteria: i. Patients with severe physical disabilities such as Spinal cord injuries, severe osteoporosis or medical conditions that prevent exercise such as ischemic changes in ECG pre-exercise. ii. Pregnant females. iii. Individuals already engaging in physical activities like athletes.

Locations (1)

CMH Bahawalpur

Chak Four Hundred Fifty-four, Punjab Province, Pakistan

RECRUITING

Outcomes

Primary Outcomes

Change in Beck Depression Inventory (BDI) score

The primary outcome will be the mean change in Beck Depression Inventory (BDI) score from baseline to the end of 06 weeks intervention period. It is a 21- item self-report scale with total scores ranging from 0 to 63. Lower scores indicate fewer depressive symptoms and therefore a better outcome. The mean change in BDI score will be compared between the aerobic exercise (plus conventional treatment ) group and the non exercise group. (conventional treatment only).

Time frame: Baseline to 06 weeks

Central Contacts

Manahil Gill, MBBS

CONTACT

+92 304 6527981 manahilgill143@gmail.com

Muhammad Ahsan Mustafa, MBBS

CONTACT

+ 92 333 3396180

Data from ClinicalTrials.gov

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