Electroencephalogram Changes Induced by Transcutaneous Electrical Acupoint Stimulation

N/ARecruitingNCT07819630

Beijing Chao Yang Hospital90 enrolled

Overview

A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group. The subjects were selected for TEAS stimulation at the Neiguan, Hegu, and Zusanli acupoints on both sides, and EEG data were collected using a 32 lead EEG cap test throughout the entire process. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Postoperative Pain

Interventions

Transcutaneous electrical acupoint stimulation

Group description: Participants in this group will receive TEAS stimulation at the bilateral Neiguan, Hegu, and Zusanli acupoints 30 minutes before the start of the surgery, and their EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, the changes in hemodynamic parameters (blood pressure, heart rate) of the subjects during surgery will be recorded, as well as the perioperative pain scores of the subjects at 1 hour and 24 hours after surgery.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria:1. Age between 18 and 80 years; 2. ASA physical status classification I-II; 3. Scheduled to undergo abdominal surgery under general anesthesia (e.g., gastrectomy, colorectal cancer surgery, etc.); 4. Consent to participate in the study and signing of the informed consent form. \- Exclusion Criteria:1. Impaired cognitive function or language communication disorders; 2. Mental disorders, epilepsy, or abnormal EEG activity; 3. Receipt of acupoint therapy within two weeks prior to surgery; 4. Presence of a cardiac pacemaker or metal implants; 5. Allergy to surface electrodes; 6. Concomitant medical conditions (e.g., dermatological disorders) that may affect treatment or trial administration. \-

Outcomes

Primary Outcomes

Electroencephalogram analysis

Changes in EEG in the experimental group with transcutaneous electrical acupoint stimulation compared to the baseline, as well as post - operative EEG changes in the experimental group and the control group.Including：node clustering coefficient，node efficiency，normalized mean clustering coefficient，normalized path length，modularity，small-world network

Time frame: Five - minute baseline EEG data with eyes closed during wakefulness；EEG data during pre - operative transcutaneous electrical acupoint stimulation；Immediate post - operative EEG data

Secondary Outcomes

Patients' VAS score

Patients' VAS scores24 hours after surgery

Time frame: 24 hours after surgery