The purpose of this study is to directly compare the efficacy of suzetrigine vs. oxycodone+acetaminophen vs. alternating acetaminophen/ibuprofen in controlling post-operative pain after the following nail unit procedures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
45
Participants will receive two 50 mg oral tablets on day 1, followed by 50 mg oral tablets every 12 hours for 5 days
Participants will receive Oxycodone + acetaminophen combination administered orally at a dose of 50 mg/325 mg per tablet, every 6 hours for 5 days starting the day of the nail procedure
Participants will receive Acetaminophen administered orally at a dose of 650 mg every 6 hours for 5 days starting the day of the nail procedure. Alternate with ibuprofen 400 mg every 6 hours for 5 days starting day of nail procedure
University of Miami, Phillip Frost Dermatology Clinic
Miami, Florida, United States
Change in Post-Operative Pain Intensity
Pot-operative pain intensity measured using the Numeric Rating Scale (NRS, 0-10), where 0 indicates no pain and 10 indicates worst possible pain; higher scores indicate greater pain following nail unit procedures.
Time frame: 24 hours post nail procedure, 48 hours post nail procedure, 72 hours post nail procedure
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