Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery

Philippine Eye Research Institute35 enrolled

Overview

The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery as well as to determine factors that could be correlated with wound seal.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cataract Surgery Cataract (Post-operative Cataract Surgery Follow-up)Phacoemulsification Cataract Surgery Wound Closure Technique Wound Closure

Interventions

Sub-Incisional PocketPROCEDURE

The sub-incisional pocket (SIP) consists of two (2) adjacent, non-penetrating, incisions using a 2.2 mm triangular blade placed just anterior to the limbus. This is followed by a penetrating clear corneal incision using the same 2.2 mm blade located immediately anterior to the SIP.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Adult (≥18 years) participants * Patients undergoing primary phacoemulsification with clear corneal incision and in-the-bag intraocular acrylic lens * Uncomplicated cataract surgeries utilizing a 2.2 mm temporal clear corneal incision with sub-incisional stromal pocket. Exclusion Criteria: * Medical records from patients with intraoperative complications requiring incisions or suturing * Prior surgery in the operative eye * Prior corneal disease or ocular surface disease * With an inadequate follow-up within 7 days after surgery

Locations (1)

Peregrine Eye and Laser Institute

Makati City, Philippines

Outcomes

Primary Outcomes

Wound seal of participants assessed with the CCI-SIP 4-point ordinal scale by pressure with cotton tip pledget at post-operative day 1.

Clear corneal incision-Subincisional pocket (CCI-SIP) wound seals were graded on a 4-point ordinal scale: Grade 4, Fully formed AC after removal of all instrumentation with no hydration maneuvers; Grade 3, Flat AC after instrumentation removal, AC reformed after hydrating the side-port incisions only; Grade 2, Flat AC reformed after hydrating both side ports and SIP; and Grade 1, flat AC reformed after hydrating the side ports, SIP and CCI lateral walls. A higher wound grade denotes better wound sealability.

Time frame: 6 Weeks

Change from 3 months pre-operation in astigmatism as measured by keratometry (diopter) at 6 weeks post-operation.

Time frame: 6 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.