Hemorrhoidal disease is a frequent benign anorectal ailment in surgical practice. Conventional excisional hemorrhoidectomy using the Milligan-Morgan technique remains effective but is significantly limited by severe postoperative pain and related complications. Sutureless hemorrhoidectomy utilizing energy-based vessel sealing devices (such as LigaSure or Harmonic Scalpel) aims to minimize tissue trauma, blood loss, and postoperative discomfort. This prospective comparative randomized clinical trial aims to evaluate and compare the perioperative and postoperative outcomes of sutureless hemorrhoidectomy versus conventional ligation hemorrhoidectomy in adult patients with advanced (grades III and IV) hemorrhoidal disease.
Symptomatic advanced hemorrhoids (grades III-IV) frequently require excisional surgical intervention. Traditional ligation techniques involve pedicle transfixion that often exacerbates postoperative pain, anal spasms, and urinary retention. Energy-based vessel sealing systems provide reliable pedicle occlusion without conventional transfixion or suture ligation, potentially expediting operative time and recovery. In this prospective randomized study conducted at the Department of General Surgery, Sohag University Hospital, 50 eligible adult patients with symptomatic grade III-IV hemorrhoidal disease will be randomly allocated (1:1) into two equal groups: Group A (n=25): Sutureless hemorrhoidectomy using an energy-based vessel sealing device. Group B (n=25): Conventional ligation hemorrhoidectomy using the standard Milligan-Morgan technique. Postoperatively, patients receive standardized analgesia and care, with systematic follow-up at 1 week, 2 weeks, 1 month, 3 months, and 6 months to evaluate pain scores, bleeding, wound healing, complication rates, return to normal activity, and symptom recurrence.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
Excision of hemorrhoidal columns with vessel pedicle sealing using an energy-based device (LigaSure or Harmonic Scalpel) without conventional pedicle transfixion or suture ligation.
Standard Milligan-Morgan hemorrhoidectomy with surgical dissection of hemorrhoidal columns and absorbable suture transfixion and ligation of vascular pedicles.
Sohag University Hospital, Department of General Surgery
Sohag, Egypt
RECRUITINGPostoperative Pain Score
Assessed using the Visual Analogue Scale (VAS) scored from 0 (no pain) to 10 (worst imaginable pain) at fixed postoperative intervals.
Time frame: Up to 6 months post-surgery
Incidence of Postoperative Bleeding
Evaluation of early or delayed postoperative perianal bleeding requiring intervention or readmission.
Time frame: Up to 6 months post-surgery
Operative Time
Duration in minutes from the initiation of tissue excision to complete surgical hemostasis.
Time frame: Intraoperative (at time of surgery)
Intraoperative Blood Loss
Estimated intraoperative blood loss measured in milliliters.
Time frame: Intraoperative (at time of surgery)
Total Postoperative Analgesic Requirement
Total analgesic dosage, type, and duration required for postoperative pain management.
Time frame: Up to 6 months post-surgery
Time to Complete Wound Healing
Clinical assessment of complete re-epithelialization of the anal wounds documented in weeks/months.
Time frame: Assessed at 1 week, 2 weeks, 1 month, 3 months, and 6 months
Length of Hospital Stay
Duration of postoperative stay in hours/days from operation until fulfilling discharge criteria.
Time frame: From surgical admission up to discharge (average 1-2 days)
Time to Return to Normal Activity
Recorded in days from surgery until the patient comfortably resumes routine daily non-strenuous activities.
Time frame: Up to 6 months post-surgery
Rate of Postoperative Complications and Recurrence
Incidence of urinary retention, wound infection, anal stenosis, continence disturbance, or symptom recurrence.
Time frame: Up to 6 months post-surgery
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