This study was conducted to compare the effects of a 12-week 16:8 Time-Restricted Feeding (Intermittent Fasting) + home-based exercise protocol with and a calorie-restricted Standard Diet (SD) + home-based exercise protocol on body composition, lipid profile, glycemic control, and liver function enzyme levels in obese women.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
66
Participants followed a 16:8 time-restricted feeding protocol (fasting for 16 hours and consuming all daily caloric intake within an 8-hour window) combined with a structured home-based exercise program for 12 weeks.
Participants followed a standard energy-restricted diet distributed across regular daily meals combined with a structured home-based exercise program for 12 weeks
Erciyes University
Kayseri, Kayseri, Turkey (Türkiye)
Change in Fasting Blood Glucose
Evaluation of changes in fasting blood glucose levels.
Time frame: Baseline and 12 weeks
Change in HOMA-IR Index
Evaluation of changes in insulin resistance index.
Time frame: Baseline and 12 weeks
Change in Lipid Profile Parameters
Evaluation of changes in serum total cholesterol, triglycerides, HDL, and LDL levels.
Time frame: Baseline and 12 weeks
Change in Serum ALT Level
Evaluation of changes in alanine aminotransferase enzyme levels.
Time frame: Baseline and 12 weeks
Change in Serum AST Level
Evaluation of changes in aspartate aminotransferase enzyme levels.
Time frame: Baseline and 12 weeks
Change in Body Mass Index (BMI)
Evaluation of changes in body mass index calculated as weight in kilograms divided by height in meters squared (kg/m²).
Time frame: Baseline and 12 weeks
Change in Body Weight
Evaluation of changes in body weight in kilograms.
Time frame: Baseline and 12 weeks
Change in Body Fat Percentage
Evaluation of changes in body fat percentage assessed via Bioelectrical Impedance Analysis (BIA).
Time frame: Baseline and 12 weeks
Change in Total Cholesterol
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Evaluation of changes in serum total cholesterol levels (mg/dL).
Time frame: Baseline and 12 weeks
Change in Triglycerides
Evaluation of changes in serum triglyceride levels (mg/dL).
Time frame: Baseline and 12 weeks
Change in HDL Cholesterol
Evaluation of changes in high-density lipoprotein cholesterol levels (mg/dL).
Time frame: Baseline and 12 weeks
Change in LDL Cholesterol
Evaluation of changes in low-density lipoprotein cholesterol levels (mg/dL).
Time frame: Baseline and 12 weeks