The main purpose of the study is to assess patient-reported satisfaction with subcutaneous (s.c.) ocrelizumab administration in participants with relapsing-remitting multiple sclerosis (RRMS) who are treatment-naive, switching from intravenous (i.v.) ocrelizumab to s.c. ocrelizumab, or switching from a prior disease-modifying therapy (DMT) to s.c. ocrelizumab.
Study Type
OBSERVATIONAL
Enrollment
1,800
Ocrelizumab will be administered at the discretion of the physician per local clinical practice and local labeling.
Proportion of Satisfied/Very Satisfied Responses on the Treatment Administration Satisfaction Questionnaire (TASQ) - Satisfaction Item Score at Month 12
Time frame: At Month 12
Proportion of Convenient / Very Convenient Responses on the TASQ Convenience Item Score at Month 12
Time frame: At Month 12
Change From Baseline in Serum Neurofilament Light Chain (NfL) at Months 6 and 12
Time frame: Baseline, Months 6 and 12
Annualized Relapse Rate (ARR) From Baseline to Month 12
Time frame: Baseline to Month 12
Proportion of Relapse-Free Participants From Baseline Through Month 12 Following Ocrelizumab s.c. Initiation
Time frame: Baseline to Month 12
Proportion of Participants Persistent on Treatment From Baseline Through Month 12
Time frame: Baseline to Month 12
Incidence, Severity and Outcomes of Adverse Events (AEs)
Time frame: Up to 2.6 years
Duration of AEs
Time frame: Up to 2.6 years
Reference Study ID Number: MN46738 https://forpatients.roche.com/ No attachments to email below.
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