This randomized clinical trial compared two different chest drain sizes, 20 Fr and 24 Fr, in patients undergoing lung lobectomy for lung cancer. The study aimed to determine whether the size of the chest drain affects postoperative recovery. Outcomes included the presence of pneumothorax and pleural effusion, postoperative pain, subcutaneous emphysema, prolonged air leak, duration of chest drainage, and length of hospital stay. A total of 80 patients were randomly assigned in a 1:1 ratio to receive either a 20-Fr or a 24-Fr chest drain.
Chest drainage is routinely used after pulmonary lobectomy to evacuate air and fluid from the pleural cavity and promote lung re-expansion. However, the optimal chest drain size after minimally invasive lung surgery remains uncertain. Smaller chest drains may improve patient comfort and reduce postoperative pain, but their ability to provide adequate pleural drainage compared with larger drains requires evaluation. This single-center, prospective, randomized interventional study compared 20-Fr and 24-Fr chest drains in patients undergoing uniportal video-assisted thoracoscopic (uVATS) lung lobectomy with systematic mediastinal lymphadenectomy for non-small cell lung cancer (NSCLC). Eligible patients were randomly assigned in a 1:1 ratio to receive either a 20-Fr or a 24-Fr thoracic drain at the end of surgery. Postoperative assessment included radiographic evaluation for pneumothorax and residual pleural effusion, as well as evaluation of subcutaneous emphysema, prolonged air leak, analgesic use, postoperative pain using the Numerical Rating Scale, chest drain duration, and length of hospital stay. The study was designed to evaluate whether chest drain size influences postoperative clinical outcomes and patient comfort following minimally invasive pulmonary lobectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
80
A 20-Fr thoracic drain was placed at the end of video-assisted thoracoscopic lobectomy. The device was used for postoperative pleural and air evacuation.
A 24-Fr thoracic drain was placed at the end of video-assisted thoracoscopic lobectomy. The device was used for postoperative pleural and air evacuation.
Fondazione Policlinico Universitario Campus Bio-Medico
Rome, Lazio, Italy
Postoperative Pneumothorax (PNX)
Presence of postoperative PNX assessed by chest X-Ray.
Time frame: Immediate postoperative period (POD0), postoperative day 1 (POD1), and postoperative day 3 (POD3)
Postoperative Pleural Effusion
Presence of residual postoperative pleural effusion assessed by chest X-Ray
Time frame: Immediate postoperative period (POD0), postoperative day 1 (POD1), and postoperative day 3 (POD3)
Postoperative Subcutaneous Emphysema
Presence of subcutaneous emphysema during the postoperative course.
Time frame: During postoperative hospitalization
Postoperative Analgesic Use
Use of analgesic medications during postoperative recovery.
Time frame: Immediately after surgery to hospital discharge
Prolonged Air Leak
Presence of postoperative air leak
Time frame: From surgery through chest drain removal, with prolonged air leak defined as lasting more than 5 postoperative days, assessed up to 30 days after surgery
Chest Drain Duration
Number of days from surgery to chest drain removal
Time frame: Immediately after surgery to chest drain removal, assessed up to 30 days after surgery
Length of Hospital Stay
Number of days from surgery to hospital discharge
Time frame: Immediate after surgery to hospital discharge, assessed up to 30 days after surgery
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Postoperative Pain
Postoperative pain intensity assessed using the 11-point Numerical Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst possible pain)
Time frame: 12, 24, and 48 hours after surgery