This retrospective cohort study aims to evaluate the effect of body mass index on the outcomes of intracytoplasmic sperm injection (ICSI) cycles at Assiut Women Health Hospital.
Obesity is associated with alterations in reproductive function and may affect the success of assisted reproductive techniques. This observational study will review medical records of women who underwent ICSI cycles. Patients will be classified according to the World Health Organization body mass index categories: underweight (\<18.5 kg/m²), normal weight (18.5-24.99 kg/m²), overweight (25-29.99 kg/m²), and obese (≥30 kg/m²). Pregnancy outcomes will be compared across BMI groups.
Study Type
OBSERVATIONAL
Enrollment
350
Clinical Pregnancy Rate After ICSI
Proportion of women achieving clinical pregnancy defined as positive serum beta-hCG and presence of gestational sac on ultrasound among total ICSI cycles stratified by BMI groups
Time frame: At 6 weeks after embryo transfer
Ongoing Pregnancy Rate
Proportion of pregnancies continuing beyond 12 weeks gestation among women who achieved clinical pregnancy stratified by BMI groups
Time frame: At 12 weeks after embryo transfer
Clinical Abortion Rate
Proportion of clinical pregnancies that result in pregnancy loss before 20 weeks gestation among BMI groups
Time frame: Up to 20 weeks after embryo transfer
Live Birth Rate
Proportion of ICSI cycles resulting in live birth among BMI groups
Time frame: At 40 weeks after embryo transfer
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