This study aims to evaluate the postoperative outcomes of pyeloplasty in pediatric patients presenting with ureteropelvic junction obstruction and preoperative differential renal function less than 10%, focusing on: * Improvement or stabilization of renal function after surgery. * Radiological improvement in hydronephrosis. * Clinical outcomes such as symptom relief and complication rates.
Ureteropelvic junction obstruction (UPJO) represents one of the most common causes of hydronephrosis in children. Historically, kidneys with differential renal function (DRF) below 10% were considered non-salvageable, and nephrectomy was often recommended. However, recent evidence suggests that pediatric renal units retain significant potential for recovery even when preoperative function is severely reduced. Numerous studies over the past decade have demonstrated that pyeloplasty in low-functioning kidneys can result in functional improvement, stabilization, and significant symptomatic relief.
Study Type
OBSERVATIONAL
Enrollment
26
Patients will undergo Anderson-Hynes dismembered pyeloplasty for primary ureteropelvic junction obstruction. The procedure was performed through an open, laparoscopic, or mini-incision approach according to the patient's age and the surgeon's clinical judgment. A ureteral stent was inserted when indicated.
Tanta University
Tanta, El-Gharbia, Egypt
RECRUITINGChange in Differential Renal Function After Pyeloplasty
Differential renal function of the affected kidney will be assessed using MAG-3 diuretic renography. Renal function will be classified as improved when differential renal function increases by at least 5 percentage points, stable when the change is less than 5 percentage points in either direction, and deteriorated when it decreases by at least 5 percentage points.
Time frame: 6 months after pyeloplasty
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