Studies of Blood Glucose and the Microbiome in Tumors and Cysts of the Pancreas

N/ANot Yet RecruitingNCT07843147

Umeå University100 enrolled

Overview

This prospective, single-center observational study investigates whether continuous glucose monitoring (CGM, 14 days) and gut microbiota composition (from a fecal sample) reveal patterns specific to pancreatic cancer, aiming to contribute to earlier detection and better assessment of disease severity. Adult patients under investigation, follow-up, or treatment for benign or malignant pancreatic/periampullary conditions are invited to participate in either or both parts of the study.

See Appendix 1 (Research Plan) for a full description of the background, aims, and methods.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Pancreatic Neoplasms Pancreatic Cysts Hyperglycemia Prediabetes

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * Adults (≥18 years of age). * Undergoing clinical investigation, follow-up, or treatment for a pancreatic or periampullary condition (malignant or benign/premalignant, including cystic lesions and pancreatitis). * Willing and able to provide written informed consent for participation in at least one component of the study (continuous glucose monitoring and/or fecal sample collection). Exclusion criteria: \-

Outcomes

Primary Outcomes

Difference in CGM-derived glycemic variability metrics

Time frame: 14 days CGM recording period

Difference in gut microbiota composition

Time frame: Single fecal sample