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Results for “Β-thalassemia”

114 trials

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Showing 20 of 114 results

Large-scale testing (Phase 3)Study completedNCT03851055
What this trial is testing

Zinc Supplementation in Patients With β-Thalassemia Major Complicated With Diabetes Mellitus

Who this might be right for
Beta-thalassemia Major Complicated With Diabetes
Ain Shams University 80
Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Very early researchActive Not RecruitingNCT06065189
What this trial is testing

Base-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia Major

Who this might be right for
Beta-Thalassemia
Children's Hospital of Fudan University 5
Not applicableStudy completedNCT06468423
What this trial is testing

Comparison of Deferasirox and Desferoxamine in Patients of β-Thalassemia Major With Iron Overload

Who this might be right for
Pateints of β-thalassemia Major With Iron Overload
RESnTEC, Institute of Research 142
Not applicableStudy completedNCT00789516
What this trial is testing

The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation

Who this might be right for
Thalassemia
Mahidol University 60
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableLooking for participantsNCT06219239
What this trial is testing

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Large-scale testing (Phase 3)Looking for participantsNCT05356195
What this trial is testing

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Who this might be right for
Beta-ThalassemiaThalassemiaGenetic Diseases, Inborn+2 more
Vertex Pharmaceuticals Incorporated 15
Not applicableUnknownNCT00481221
What this trial is testing

Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter

Who this might be right for
ThalassemiaIron Deficiency
HaEmek Medical Center, Israel 30,000
Not applicableUnknownNCT05370677
What this trial is testing

The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University Hospitals

Who this might be right for
Beta-Thalassemia
Assiut University 141
Testing effectiveness (Phase 2)Looking for participantsNCT07292259
What this trial is testing

Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Pakistan Blood and Marrow Transplant (PBMT) Group 150
Not applicableStudy completedNCT04211480
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
β Thalassemia Major
Bioray Laboratories 6
Not applicableNot Yet RecruitingNCT07215975
What this trial is testing

A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East

Who this might be right for
β-thalassemia
Bristol-Myers Squibb 200
Testing effectiveness (Phase 2)Ended earlyNCT04059406
What this trial is testing

Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)

Who this might be right for
Beta Thalassemia Intermedia
Ionis Pharmaceuticals, Inc. 29
Large-scale testing (Phase 3)Study completedNCT02604433
What this trial is testing

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia

Who this might be right for
Erythrocyte TransfusionBeta-Thalassemia
Celgene 336
Post-approval studies (Phase 4)Active Not RecruitingNCT05891249
What this trial is testing

Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

Who this might be right for
Anemia
Bristol-Myers Squibb 85
Post-approval studies (Phase 4)WithdrawnNCT01724138
What this trial is testing

An Open Label Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Efficacy of Deferasirox Administered to Chinese Patients With β-thalassemia Major Aged From 2 to Less Than 6 Years Old

Who this might be right for
β-thalassemia Major
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT04143724
What this trial is testing

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Who this might be right for
Beta-Thalassemia
Celgene 99
Testing effectiveness (Phase 2)UnknownNCT03014882
What this trial is testing

Sperm DNA Damage in β-thalassemia Major: Is There a Role for Antioxidants?

Who this might be right for
Endocrine DiseaseFertility Decreased MaleDNA Damage
Ain Shams University 30
Large-scale testing (Phase 3)Study completedNCT06146478
What this trial is testing

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Blood Care Clinic 200
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