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Results for “β -Thalassemia”

117 trials

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Showing 20 of 117 results

Very early researchUnknownNCT03728322
What this trial is testing

IHSCs With the Gene Correction of HBB Intervent Subjests With β-thalassemia Mutations

Who this might be right for
Thalassemia
Allife Medical Science and Technology Co., Ltd. 12
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Testing effectiveness (Phase 2)Looking for participantsNCT06280378
What this trial is testing

Β-Thalassemia Treatment with KL003 Cell Injection

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd. 41
Testing effectiveness (Phase 2)Ended earlyNCT04205435
What this trial is testing

Β-globin Restored Autologous HSC in β-thalassemia Major Patients

Who this might be right for
β-thalassemia Major
Bioray Laboratories 2
Not applicableUnknownNCT01905787
What this trial is testing

Sickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter Study

Who this might be right for
Sickle Cell AnemiaSickle Cell β+ or β0 Thalassemia
HaEmek Medical Center, Israel 300
Testing effectiveness (Phase 2)Looking for participantsNCT05736419
What this trial is testing

Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Who this might be right for
Sickle Cell DiseaseThalassemia, BetaThalassemia
Memorial Sloan Kettering Cancer Center 24
Not applicableUnknownNCT03101423
What this trial is testing

Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism

Who this might be right for
Beta Thalassemia Major
First Affiliated Hospital of Guangxi Medical University 30
Testing effectiveness (Phase 2)Study completedNCT01745120
What this trial is testing

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

Who this might be right for
β-thalassemia Major
Genetix Biotherapeutics Inc. 19
Post-approval studies (Phase 4)UnknownNCT01846923
What this trial is testing

B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic Individuals

Who this might be right for
Aspleniaβ-thalassemia Major
Aghia Sophia Children's Hospital of Athens 37
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableStudy completedNCT04211480
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
β Thalassemia Major
Bioray Laboratories 6
Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Not applicableLooking for participantsNCT07207577
What this trial is testing

Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD

Who this might be right for
Beta Thalassemia Transfusion Dependent
Centre Hospitalier Metropole Savoie 36
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Large-scale testing (Phase 3)Study completedNCT00171210
What this trial is testing

An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload

Who this might be right for
Transfusional Iron Overload in β-thalassemia
Novartis Pharmaceuticals 506
Not applicableLooking for participantsNCT06271512
What this trial is testing

Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 150
Very early researchEnrolling By InvitationNCT06328764
What this trial is testing

CS-101 in Patients With β-thalassemia

Who this might be right for
Beta-Thalassemia
CorrectSequence Therapeutics Co., Ltd 10
Testing effectiveness (Phase 2)Study completedNCT01749540
What this trial is testing

Study to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002)

Who this might be right for
B-Thalassemia
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 64
Not applicableActive Not RecruitingNCT06596642
What this trial is testing

A Real-World Study of β-Thalassemia Major Treatment With Luspatercept in Taiwan

Who this might be right for
β-Thalassemia Major
Bristol-Myers Squibb 61
Not applicableLooking for participantsNCT06314529
What this trial is testing

Long-term Follow-up Study of BHC001 for TDT

Who this might be right for
Thalassemia, Beta
Bioray Laboratories 6
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