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Results for “β Thalassemia Major”

96 trials

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Showing 20 of 96 results

Large-scale testing (Phase 3)Looking for participantsNCT07506863
What this trial is testing

Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Who this might be right for
Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 54
Testing effectiveness (Phase 2)Ended earlyNCT04411082
What this trial is testing

IMR-687 in Subjects With Beta Thalassemia

Who this might be right for
β Thalassemia
Cardurion Pharmaceuticals, Inc. 122
Post-approval studies (Phase 4)Study completedNCT03961828
What this trial is testing

Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C Virus

Who this might be right for
Beta-ThalassemiaHepatitis C
Tanta University 50
Not applicableUnknownNCT05370677
What this trial is testing

The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University Hospitals

Who this might be right for
Beta-Thalassemia
Assiut University 141
Large-scale testing (Phase 3)Study completedNCT06153784
What this trial is testing

Thalidomide and Hydroxyurea Combination in β-Thalassemia Patients

Who this might be right for
Thalassemia, Beta
Children's Hospital Karachi 603
Testing effectiveness (Phase 2)Active Not RecruitingNCT06421636
What this trial is testing

Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Who this might be right for
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT05567458
What this trial is testing

Evaluate Luspatercept (ACE-536) in Chinese Participants Who Require Regular Red Blood Cell Transfusions Due to Beta (β)-Thalassemia.

Who this might be right for
Beta-thalassemia
Bristol-Myers Squibb 94
Not applicableEnded earlyNCT05752123
What this trial is testing

Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects with Transfusion Dependent Β-Thalassaemia.

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 2
Not applicableActive Not RecruitingNCT06596642
What this trial is testing

A Real-World Study of β-Thalassemia Major Treatment With Luspatercept in Taiwan

Who this might be right for
β-Thalassemia Major
Bristol-Myers Squibb 61
Testing effectiveness (Phase 2)Study completedNCT01044186
What this trial is testing

A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity

Who this might be right for
Transfusional Iron Overload
Novartis Pharmaceuticals 30
Very early researchStudy completedNCT06024876
What this trial is testing

A Clinical Study Evaluating the Safety and Efficacy of CS-101 in Treating Subjects With β-thalassemia

Who this might be right for
Beta-Thalassemia
CorrectSequence Therapeutics Co., Ltd 5
Not applicableUnknownNCT03847558
What this trial is testing

Sexual Maturation in β-Thalassemia Major Patients in Assiut University Hospital

Who this might be right for
β-Thalassemia Major Patients Receiving Chelation Therapy
Assiut University 100
Not applicableStudy completedNCT05015920
What this trial is testing

A Study Evaluating the Safety and Efficacy of the BD211 Drug Product in β-Thalassemia Major Participants

Who this might be right for
Hematologic Diseases
Shanghai BDgene Co., Ltd. 2
Early research (Phase 1)Looking for participantsNCT06647979
What this trial is testing

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)Beta-Thalassemia+1 more
Daniel Bauer 10
Not applicableTemporarily pausedNCT05442346
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
Thalassemia Major
Bioray Laboratories 5
Testing effectiveness (Phase 2)Ended earlyNCT04205435
What this trial is testing

Β-globin Restored Autologous HSC in β-thalassemia Major Patients

Who this might be right for
β-thalassemia Major
Bioray Laboratories 2
Testing effectiveness (Phase 2)Study completedNCT01749540
What this trial is testing

Study to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002)

Who this might be right for
B-Thalassemia
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 64
Not applicableUnknownNCT06041620
What this trial is testing

Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells

Who this might be right for
Thalassemia, BetaThalassemia Major
Institute of Hematology & Blood Diseases Hospital, China 2
Testing effectiveness (Phase 2)Looking for participantsNCT04143724
What this trial is testing

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Who this might be right for
Beta-Thalassemia
Celgene 99
Not applicableLooking for participantsNCT06314529
What this trial is testing

Long-term Follow-up Study of BHC001 for TDT

Who this might be right for
Thalassemia, Beta
Bioray Laboratories 6
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